AbstractObjectivesThe aim of this review is to ascertain whether Bojungikgi-tang and its modifications is more effective than non-specific management in chronic fatigue syndrome (CFS).
MethodsWe collected clinical trials to investigate the effects of Bojungikgi-tang and non-specific management on general symptoms, fatigue, and sleep quality in CFS patients. The databases used for data retrieval were Pubmed, Central Cochrane, CNKI, VIP, CiNii, OASIS, RISS, and Koreamed. We performed selection/exclusion process from the found records according to prespecified criteria, and assessed the final included trials according to the Cochrane risk of bias tool. The included studies were classified on the basis of interventions in experimental group.
ResultsSeven randomized controlled trials (476 participants) were eligible and their results were synthesized in the meta-analysis. The synthesis showed a substantial effect of Bojungikgi-tang (relative risk 0.20 [95% CI 0.13 to 0.31], Z=7.44, P<0.00001; I2=0%) and combination of Bojungikgi-tang and Sosiho-tang (relative risk 0.15 [95% CI 0.08 to 0.28], Z=5.85, P<0.00001; I2=0%) compared with non-specific management on improvement of general symptoms. However, we could not find sufficient clinical research records to determine their effects of improvement on fatigue and sleep quality.
참고문헌1. Fukuda K, Straus SE, Hickie I, Sharpe MC, Dobbins JG, Komaroff A. The chronic fatigue syndrome: a comprehensive approach to its definition and study. International Chronic Fatigue Syndrome Study Group [see comments]. Ann Intern Med. 1994; 121:12. 953–9.
2. Holmes GP, Kaplan JE, Gantz NM, Komaroff AL, Schonberger LB, Straus SE, et al. Chronic fatigue syndrome: A working case definition. Ann Intern Med. 1988; 108:3. 387–9.
3. Meirleir KL, De Peterson DL, Klimas NG, Lerner aM, Bested AC, Sherkey Ja, et al. Myalgic encephalomyelitis/chronic fatigue syndrome: clinical working case definition, diagnostic and treatment protocols. J Chronic Fatigue Syndr. 2003; 11:1. 7–97.
4. Sharpe MC, Archard LC, Banatvala JE, Borysiewicz LK, Clare AW, David A, et al. A report - chronic fatigue syndrome: guidelines for research. J R Soc Med. 1991; 84:2. 118–21.
5. Jason LA, Brown A, Clyne E, Bartgis L, Evans M, Brown M. Contrasting case definitions for chronic fatigue syndrome, Myalgic Encephalomyelitis/chronic fatigue syndrome and myalgic encephalomyelitis. Eval Health Prof. 2012; 35:3. 280–304.
6. Carruthers BM, Sande MI, van de Meirleir KL, De Klimas NG, Broderick G, Mitchell T, et al. Myalgic encephalomyelitis: International Consensus Criteria. J Intern Med. 2011; 270:4. 327–38.
7. Committee on the diagnostic criteria for myalgic encephalomyelitis/chronic fatigue syndrome. Beyond myalgic encephalomyelitis/chronic fatigue syndrome. Washington, D.C: National Academies Press;2015.
8. Kwak K, Cho J, Son C. Study on chronic fatigue syndrome from Oriental medicine point of view. Korean J Orient Intern Med. 2008; 29:4. 962–969.
9. Kim JW, Kim HJ, Jang ES, Jung H, Hwang MW, Nam DH. Survey on pattern identification and treatment of chronic fatigue in Korea medicine. J Physiol Pathol Korean Med. 2018; 32:2. 126–33.
10. Reeves WC, Wagner D, Nisenbaum R, Jones JF, Gurbaxani B, Solomon L, et al. Chronic fatigue syndrome - a clinically empirical approach to its definition and study. BMC Med. 2005; 3:19
11. Treatment of ME/CFS. Centers Dis Control Prev. 2018.
https://www.cdc.gov/me-cfs/treatment/index.html
12. Hundertmark JD, Hickie IB, Beard DD, Larkins RG, Molesworth SR. Chronic fatigue syndrome clinical practice guidelines: Psychological factors. Med J Aust. 2002; 177:9. 525–7.
13. Chronic fatigue syndrome/myalgic encephalomyelitis (or encephalopathy): diagnosis and management. Clinical guideline. 2007; CG53
14. Chen R, Moriya J, Yamakawa JI, Takahashi T, Kanda T. Traditional chinese medicine for chronic fatigue syndrome. Evid Based Complement Alternat Med. 2010; 7:1. 3–10.
15. Adams D, Wu T, Yang X, Tai S, Vohra S. Traditional Chinese medicinal herbs for the treatment of idiopathic chronic fatigue and chronic fatigue syndrome. Cochrane database Syst Rev. 2009; 4. CD006348
16. Adams D, Wu T, Yang X, Tai S, Vohra S. Traditional Chinese medicinal herbs for the treatment of idiopathic chronic fatigue and chronic fatigue syndrome. Cochrane Database Syst Rev. 2018.
17. Wang YY, Li XX, Liu JP, Luo H, Ma LX, Alraek T. Traditional Chinese medicine for chronic fatigue syndrome: A systematic review of randomized clinical trials. Complement Ther Med. 2014; 22:4. 826–33.
18. Liu Q. Discussion on the therapeutic effect of traditional Chinese medicine diagnosis and treatment of chronic fatigue syndrome. Foreign Med Sci. 1993; 15:6. 15
19. Zheng YY. Guiding principles for clinical research of new drugs in traditional Chinese medicine. Beijing: China Medical Science and Technology Press;2002.
20. Higgins J, Green S. Cochrane handbook for systematic reviews of interventions ver 5.1.0. The cochrane collaboration;2011.
21. Guyatt GH, Oxman AD, Vist GE, Kunz R, Falck-Ytter Y, Alonso-Coello P, et al. GRADE: an emerging consensus on rating quality of evidence and strength of recommendations. BMJ. 2008; 336:7650. 924–6.
22. Kim S, Park J, Seo H, Lee Y, Jang B, Son H, et al. NECA’s guidance for undertaking systematic reviews and meta-analyses for intervention. National evidence-based healthcare collaborating agency;2011.
23. Shu Y, Zhang G. Treatment of 30 cases of chronic fatigue syndrome with buzhongyiqi decoction. J Anhui Tradit Chinese Med Coll. 1997; 16:5. 11
24. Yang S, Gao M, Yang X, Chen D. Clinical observation of the treatment of chronic fatigue syndrome by using buzhongyiqi decoction in combination with xiaochaihu decoction. J Beijing Univ Tradit Chinese Med. 2004; 27:2. 87–9.
25. Jiang Q. Therapeutic effect of buzhongyiqi decoction and guipi decoction on chronic fatigue syndrome. Beijing J Tradit Chinese Med. 2012; 2:31. 121–2.
26. Tian H, Wang S. Treatment of 32 cases of chronic fatigue syndrome with buzhongyiqi decoction. Jiangxi J Tradit Chinese Med. 2012; 43:8. 26–7.
27. Wang H. Clinical study on buzhongyiqi decoction and xiaochaihu decoction in treating chronic fatigue syndrome. Asia-Pacific Tradit Med. 2012; 8:8. 67–8.
28. Teng F, Jiang Q, Huang Y. Therapeutic effect of buzhongjieliu decoction on chronic fatigue syndrome. Guid J Tradit Chinese Med Pharm. 2014; 20:4. 108–10.
29. Li Y. Clinical observation on treatment of chronic fatigue syndrome with liver depression and spleen deficiency syndrome by buzhongyiqi decoction and xiaochaihu decoction. Asia-Pacific Tradit Med. 2015; 11:17. 124–5.
30. Vincent A, Brimmer DJ, Whipple MO, Jones JF, Boneva R, Lahr BD, et al. Prevalence, incidence, and classification of chronic fatigue syndrome in Olmsted county, Minnesota, as estimated using the Rochester epidemiology project. Mayo Clin Proc. 2012; 87:12. 1145–52.
31. Kim CH, Shin HC, Pak YW. The prevalence of chronic fatigue and chronic fatigue syndrome: A hospital based study. J Korean Acad Fam Med. 2000; 21:10. 1288–98.
32. Ko KM, Leon TYY, Mak DHF, Chiu PY, Du Y, Poon MKT. A characteristic pharmacological action of ‘Yang-invigorating’ Chinese tonifying herbs: enhancement of myocardial ATP-generation capacity. Phytomedicine. 2006; 13:9–10. 636–42.
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