A case report of gastrointestinal perforation in patient after biliary stent insertion and the overview of gastrointestinal perforation

Article information

J Korean Med. 2022;43(3):195-203
Publication date (electronic) : 2022 September 1
doi : https://doi.org/10.13048/jkm.22040
1Dept. of Hepatology & hematology, College of Korean medicine, Daejeon University
2East-West Cancer Center, Cheonan Korean Medicine Hospital, Daejeon University
3Liver and Immunology Research Center, Daejeon Korean Medicine Hospital of Daejeon University
Correspondence to: Nam-hun Lee, Dongseo Cancer Center, Cheonan Oriental Medicine Hospital, Daejeon University, Notaesan-ro 4-gil, Seobuk-gu, Cheonan-si, Tel:+82-41-521-7536, Fax:+82-41-521-7007, E-mail: nhlee@dju.kr
Received 2022 May 25; Revised 2022 July 26; Accepted 2022 August 16.

Abstract

Objectives

This study aimed to emphasize the importance of accurate and timely diagnosis of acute abdominal pain with simple radiography by reporting a case of gastrointestinal perforation.

Methods

We closely observed the diagnosis and progress of acute abdominal pain after biliary stent and reviewed the outline of gastrointestinal perforation.

Results

Patient diagnosed with urethral cancer metastasis to lung and peritoneum was treated with complex Korean medicinal treatments to deal with anorexia, abdominal pain, jaundice and oliguria. During hospitalization, the patient’s acute abdominal pain after biliary stent was diagnosed with gastrointestinal perforation by using plain chest and abdominal radiography.

Conclusion

Using simple radiography to find out the emergency diseases such as perforation in acute abdominal pain is important clinically.

Fig. 1

Computed Tomography(CT) at diagnosis (2019.02.21.) A: Abdomen CT, B: Chest CT

Fig. 2

Summary of treatment course.

Fig. 3

Changes of LFT and bilirubin after PTBD

Fig. 4

Changes of vital sign and patient’s progress

Fig. 5

Simple X-rays when diagnosed with perforation (2019.03.29)

A: Chest X-ray B: Abdomen S/E

Biochemical data of the patient

Changes of vital sign during administration period

References

1. Brewer B.J., Golden G.T., Hitch D.C., Rudolf S.L., ; Abdominal pain. 1976;An analysis of 1,000 consecutive cases in a University Hospital emergency room. Am J Surg 131:219–23. 10.1016/0002-9610(76)90101-x.
2. Powers R.D., Guertler A.T.. 1995;Abdominal pain in the ED: stability and change over 20 years. Am J Emerg Med 13:301–3. 10.1016/0735-6757(95)90204-X.
3. Jong W.C., Joo Y.S., Hong K., Chang S.R., Sung M.L., Yang G.J., et al. 1997;The Value of CT in Detecting Pathologic Bowel Perforation. J Korean Radiol Soc 37:697–702.
4. Kwack H.J., Kim K.M., Kim M.H., Jin G.Y., Chung M.J.. 2011;Pneumatosis intestinalis and Intestinal perforation related to Rapid Response during Sunitinib Therapy for Gastrointestinal stromal tumor. The Chonbuk Univ Med J 35(1):39–43.
5. Oh J.H., Lee I.S.. 2007;Image of The Month: Enterovesical Fistula and Intestinal Perforation Complicated by Crohn’s Disease. The Korean J Gastroenterol 49(4):199–200.
6. Choi W.Y., Choi J.Y., Lee J.H., Seo C.J., Park K.W., Park S.H., et al. 2007;Remission of Refractory Intestinal Behcet’s Disease with Infliximab. J Rheum Dis 14(1):61–5.
7. Kim M.H., Lee S.S., Park D.H., Lee S.K., Kim H.J., Seo D.W., et al. 2011;Case Report: Three Cases of Successful Treatment of Iatrogenic Duodenal Perforation. The Korean J Gastrointestinal Endoscopy 42(1):57–61.
8. Tanner T.N., Hall B.R., Oran J.. 2018;Pneumoperitoneum. Surg. Clin. North Am 98(5):915–32. 10.1016/j.suc.2018.06.004.
9. Mayumi T., Yoshida M., Tazuma S., Furukawa A., Nishii O., Shigematsu K., et al. 2016;The Practice Guidelines for Primary Care of Acute Abdomen 2015. Jpn J Radiol 34(1):80–115. 10.1007/s11604-015-0489-z. 26678269.
10. Stapfer M., Selby R.R., Stain S.C.. 2000;Management of duodenal perforation after endoscopic retrograde cholangiopancreatography and sphincterotomy. Ann Surg 232:191–8. 10.1097/00000658-200008000-00007.
11. Enns R., Eloubeidi M.A., Mergener K., Jowell P.S., Branch M.S., Pappas T.M., et al. 2002;ERCP-related perforations: risk factors and management. Endoscopy 34:293–8. 10.1055/s-2002-23650.
12. Kumar A., Muir M.T., Cohn S.M., Salhanick M.A., Lankford D.B., Katabathina V.S.. 2012;The etiology of pneumoperitoneum in the 21st century. J Trauma Acute Care Surg 73:542–8. 10.1097/TA.0b013e31825c157f.
13. Levine M.S., Scheiner J.D., Rubesin S.E., Laufer I., Herlinger H.. 1991;Diagnosis of pneumoperitoneum on supine abdominal radiographs. AJR Am J Roentgenol 156:731–5. 10.2214/ajr.156.4.2003436.
14. Stapakis J.C., Thickman D.. 1992;Diagnosis of pneumoperitoneum: abdominal CT vs. upright chest film. J Comput Assist Tomogr. 16(5):713–6.
15. Park J.M., Yoon Y.H., Horeczko T., Kaji A.H., Lewis R.J.. 2017;Changes of Clinical Practice in Gastrointestinal Perforation with the Increasing Use of Computed Tomography. J Korean Soc Traumatol 30(2):25–32.
16. Damore L.J., Rantis P.C., Vernava A.M., Longo W.E.. 1996;Colonoscopic perforations. Etiology, diagnosis, and management. Dis Colon Rectum 39(11):1308–14. 10.1007/BF02055129.
17. Cai S.L., Chen T., Yao L.Q., Zhong Y.S.. 2015;Management of iatrogenic colorectal perforation: From surgery to endoscopy. World J Gastrointest Endosc 7(8):819–23. 10.4253/wjge.v7.i8.819.
18. Park J.W., Yoon J., Cho C.K., Lee Y.W., Yoo H.S.. 2014;Survival analysis of stage IV metastatic gastric cancer patients treated with HangAm-Plus. Chin J Integr Med 20(1):49–55. 10.1007/s11655-012-1084-0.
19. Khan N., Afaq F., Syed D.N., Mukhtar H.. 2008;Fisetin, a novel dietary flavonoid, causes apoptosis and cell cycle arrest in human prostate cancer LNCaP cells. Carcinogenesis 29(5):1049–56. 10.1093/carcin/bgn078.
20. Suh Y., Afaq F., Johnson J.J., Mukhtar H.. 2009;A plant flavonoid fisetin induces apoptosis in colon cancer cells by inhibition of COX2 and Wnt/EGFR/NF-kappaB-signaling pathways. Carcinogenesis 30(2):300–7. 10.1093/carcin/bgn269.
21. Yim M.H., Shin J.W., Son J.Y., Oh S.M., Han S.H., Cho J.H., et al. 2007;Soluble components of Hericium erinaceum induce NK cell activation via production of interleukin-12 in mice splenocytes. Acta Pharmacol Sin 28(6):901–907. 2007;10.1111/j.1745-7254.2007.00577.x.
22. Lee G.Y., Park C.R., Cho J.H., Son C.G., Lee N.H.. 2020;The Effect of Chunggan Plus Extract in Improving Liver Function: A Retrospective Case Series of Eight Patients. J Int Korean Med 41(3):542–51. http://dx.doi.org/10.22246/jikm .
23. Srinivasan I., Kahaleh M.. 2011;Biliary stents in the millennium. Adv Ther 28(11):960–72. 10.1007/s12325-011-0067-4.
24. Mady R.F., Niaz O.S., Assal M.M.. 2015;Migrated biliary stent causing perforation of sigmoid colon and pelvic abscess. BMJ Case Rep 2015;:bcr2014206805. 10.1136/bcr-2014-206805.
25. Eisenberg R.L., Heineken P., Hedgcock M.W., Federle M., Goldberg H.I.. 1983;Evaluation of plain abdominal radiographs in the diagnosis of abdominal pain. Ann Surg 197(4):464–9. 10.1097/00000658-198304000-00016.

Article information Continued

Fig. 1

Computed Tomography(CT) at diagnosis (2019.02.21.) A: Abdomen CT, B: Chest CT

Fig. 2

Summary of treatment course.

Fig. 3

Changes of LFT and bilirubin after PTBD

Fig. 4

Changes of vital sign and patient’s progress

Fig. 5

Simple X-rays when diagnosed with perforation (2019.03.29)

A: Chest X-ray B: Abdomen S/E

Table 1

Biochemical data of the patient

Parameter 2019-03-11 2019-03-15 2019-03-28
AST(IU/L) 158 162 60
ALT(IU/L) 69 80 22
ALP(IU/L) 279 292 164
Total bilirubin(mg/dL) 3.65 5.71 2.57
Direct bilirubin(mg/dL) 2.8 4.7 1.8

Table 2

Changes of vital sign during administration period

Parameter Blood pressure Pulse rate Body temperature
03-28 02:00 120/70 90 37.1
03-28 06:00 120/70 63 37.1
03-28 10:00 120/70 82 37
03-28 14:00 120/70 86 36.5
03-28 18:00 120/80 76 36.7
03-28 21:00 130/70 90 36.5
03-29 02:00 140/80 84 36.9
03-29 06:00 130/80 91 36.9
03-29 10:00 120/80 96 37

03-29 14:00 130/80 105 36.4