AbstractBone mineral density (BMD) is a major diagnostic marker for bone health. A 44-year-old male had BMD of 0.81 g/cm2 (Z-score: −3.1) in lumbar spine scan and 0.54 g/cm2 (Z-score: −2.7) for femoral neck from regular medical checkup in Apr 2020. He had no other specific medical conditions except hyperlipidemia and alcohol was a single risk factor for fracture according to Fracture Risk Assessment Tool. After he was diagnosed with liver-kidney deficiency and treated for 20 weeks with Jeopgol-tang originally patented for promoting fracture recovery, lumbar spine BMD increased by 13.6 % (0.92 g/cm2, Z-score: −2.1) and femoral neck BMD by 22.2% (0.66 g/cm2, Z-score: −1.8) compared with those of Mar 2020. Herbal medicine treatment for tonifying liver and kidney to improve BMD warrants further investigation.
참고문헌1. Consensus development conference: diagnosis, prophylaxis, and treatment of osteoporosis. Am J Med. 1993; 94:6. 646–50.
2. Assessment of fracture risk and its application to screening for postmenopausal osteoporosis. Report of a WHO Study Group. World Health Organ Tech Rep Ser. 1994; 843:1–129.
3. Mauck KF, Clarke BL. Diagnosis, screening, prevention, and treatment of osteoporosis. Mayo Clin Proc. 2006; 81:5. 662–72.
4. Johnell O, Kanis JA, Odén A, Sernbo I, Redlund-Johnell I, Petterson C, De Laet C, Jönsson B. Mortality after osteoporotic fractures. Osteoporos Int. 2004; Jan. 15:1. 38–42.
5. Ha YC, Kim TY, Lee A, Lee YK, Kim HY, Kim JH, et al. Current trends and future projections of hip fracture in South Korea using nationwide claims data. Osteoporos Int. 2016; 27:8. 2603–9.
6. Kim J, Lee E, Kim S, Lee TJ. Economic Burden of Osteoporotic Fracture of the Elderly in South Korea: A National Survey. Value Health Reg Issues. 2016; 9:36–41.
7. Kanis J. Assessment of osteoporosis at the primary health-care level Technical Report: WHO Collaborating Centre. University of Sheffield;2008. [cited Nov 2020]. Available from: http://www.shef.ac.uk/FRAX
8. Cosman F, de Beur SJ, LeBoff MS, Lewiecki EM, Tanner B, Randall S, et al. Clinician’s Guide to Prevention and Treatment of Osteoporosis. Osteoporos Int. 2014; 25:10. 2359–81.
9. Mikyas Y, Agodoa I, Yurgin N. A systematic review of osteoporosis medication adherence and osteoporosis-related fracture costs in men. Appl Health Econ Health Policy. 2014; 12:3. 267–77.
10. Zhao JG, Zeng XT, Wang J, Liu L. Association Between Calcium or Vitamin D Supplementation and Fracture Incidence in Community-Dwelling Older Adults: A Systematic Review and Meta-analysis. JAMA. 2017; 318:24. 2466–82.
11. Liu Y, Liu JP, Xia Y. Chinese herbal medicines for treating osteoporosis. Cochrane Database Syst Rev. 2014; 3. CD005467
12. Yun G, Kang J, Lee H. Effects of Korean herbal medicine (Cheong-A-Won) for treatment of bone mineral density in women with osteoporosis: A randomized, double blind, placebo controlled trial. Eur J Integr Med. 2018; 20:84–9.
13. Guide publishing group of Korean society for bone and mineral research. Physician’s guide for osteoporosis. Seoul: Cdmthebig;2018.
14. Department of kidney internal medicine. Kidney Internal Medicine. Seoul: Gunjachulpansa;2015. p. 116–20.
15. In : Lee H, Hahm D, Kim H, Sohn B, Hwang D, Choi Y, editors. The effect of Jeopgol-tang on recovery of bone fracture in Sprague-Dawley rats. The Annual Conference of Traditional Korean Medicine; 2006.
16. Lee H, Hahm D, Kim H, Sohn B, Choi Y, DSH . Crude drugs composition for accelerating recovery of bone fracture. 10-0731160. 2007.
17. Leutner M, Matzhold C, Bellach L, Deischinger C, Harreiter J, Thurner S, et al. Diagnosis of osteoporosis in statin-treated patients is dose-dependent. Ann Rheum Dis. 2019; 78:12. 1706–11.
18. Hong S, You S. A study of prevalence and related risk factors of osteoporosis for employees. JKIECS. 2013; 8:4. 631–7.
19. Han G, Kim S. What Cases Are Worth Publishing in the Korean Medical Case Report? Korean J Acupunct. 2020; 37:3. 159–71.
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