| 항암화학요법 관련 인지장애에 대한 침술 임상연구 동향 분석: 주제범위 문헌 고찰 |
김미경1 
, 한창호2
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1동국대학교일산한방병원 한방내과
2동국대학교 한의과대학 내과학교실 |
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| Trends in clinical trials of acupuncture for chemotherapy-related cognitive impairment: A Scoping Review |
| Mikyung Kim1
, and Chang-ho Han2
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1Department of Internal Medicine, Dongguk University Ilsan Oriental Hospital
2Department of Internal Medicine, College of Korean Medicine, Dongguk University WISE Campus |
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| Corresponding Author:
Mikyung Kim ,Tel: +82-31-961-9045, Email: 01mkkim@gmail.com |
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Received: January 19, 2025; Revised: February 17, 2025. Accepted: February 17, 2025. |
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| ABSTRACT |
Objectives: This study was aimed to review and analyze trends in clinical trials of acupuncture for chemotherapy-related cognitive impairment (CRCI).
Methods: On December 20, 2024, three core databases (PubMed, Embase, and Cochrane Library), the International Clinical Trials Registry Platform, and ClinicalTrials.gov were searched to obtain clinical trial reports and protocols that evaluated the effects of acupuncture on cognitive function in patients with CRCI.
Results: A total of five reports and six protocols were retrieved. All five reports were conducted in East Asia, including China, Hong Kong, and Korea, and only two of them were randomized controlled trials (RCTs). These studies suggest that acupuncture may be beneficial in improving CRCI. All protocols were RCTs, and were scheduled to be conducted in China, Italy, and the United States. Most of them planned to conduct cognitive function tests but also measure biomarkers.
Conclusion: Only a few small trials have been published so far, even though they claimed results supporting the benefit of acupuncture. Current RCTs that are ongoing or planned to be conducted tend to be larger in scale and more diverse in quality compared to previous trials. Therefore, it is expected that we will soon be able to secure the evidence necessary to draw more definitive conclusions about the effect of acupuncture on CRCI. However, future trials need to be carefully designed to complement the limitations of existing reports and protocols. |
| Keywords:
chemotherapy-related cognitive impairment | chemotherapy-induced cognitive impairment | chemobrain | chemofog | acupuncture | review |
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