Three Cases of Oral Mucoceles Treated with Traditional Korean Medicine

Article information

J Korean Med. 2016;37(3):123-130
Publication date (electronic) : 2016 September 30
doi : https://doi.org/10.13048/jkm.16040
1Kyungheeyedang Oriental Medical Clinic
2Department of Korean medical science, School of Korean Medicine, Pusan national university Clinical research division, Korea Institute of Oriental Medicine
3Department of integrative medicine, School of Korean Medicine, Pusan national university
Correspondence to: 윤영주 (Youngju Yun), 경남 양산시 물금읍 금오로 20, 부산대학교 한의학전문대학원, Tel: +82-55-360-5955, Fax: +82-55-360-5909, E-mail: mdkmdyun@pusan.ac.kr
Received 2016 July 04; Revised 2016 September 22; Accepted 2016 September 22.

Abstract

This is the first case report about oral mucoceles treated with traditional Korean medication in Korea. One case of Blandin-Nuhn mucocele and two cases of ranula were treated with Ondam-tang and Dohongsamul-tang respectively. No recurrence of ranula was found for 30 months in one case and 3 months in other recent case. According to this result, we suppose that consideration of “Blood stasis and heat” might be helpful to treat progressed or large mucoceles while common mucoceles are generally regarded as results of “Phlegm heat”. We suggest that traditional Korean medication can be an alternative to preserve salivary glands and to minimize complications of surgery. Further studies with more cases and longer observation period should be performed to establish proper prescriptions for oral mucocele and the evidence of treatment rate and recurrence rate.

Fig. 1

Photographs of Clinical Changes of Case 1.

A: 2013-05-11. Ranula on the right sublingual area, sized approximately 1.2cm×1.2cm.

B: 2013-08-31. No shrinkage was observed compared with A.

C: 2013-10-05. More than 50% shrinkage was observed.

D: 2013-11-26. The ranula was completely shrunk.

Fig. 2

Photographs of Clinical Changes of Case 2.

A: 2015-11-23. Sublingual mucocele sized 1.0×1.1cm was observed.

B: 2015-12-12. The size was reduced to nearly 0.5×0.8cm.

C: 2016-01-02. The size was approximately 0.4×0.6cm.

D: 2016-01-23. The sublingual mucocele nearly disappeared.

Fig. 3

Photographs of Clinical Changes of Case 3.

A: 2016-01-23. Plunging ranula about 3cm diameter was observed in the left submandibular area.

B: 2016-02-04. The diameter of the plunging ranula decreased to about 2.0cm.

C: 2016-02-22. The mass was not observed.

Fig. 4

Ultrasonography of Case 3 on 2016-03-09.

The ultrasonography revealed there was no mass around the left submandibular gland. The picture only showed trace of inflammation with low-echo.

References

1. Baurmash HD. Mucoceles and ranulas. Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons 2003;61(3):369–78.
2. Harrison J. Salivary mucoceles. Oral Surgery, Oral Medicine, Oral Pathology 1975;39(2):268–78.
3. Park SG, Park NS, Cho CS, Kim AY, Chang DS, Lee HY, et al. Clinical and histological analysis of oral mucocele. Korean J Otorhinolaryngol-Head Neck Surg 2013;56(6):359–64.
4. Adachi P, Soubhia AM, Horikawa FK, Shinohara EH. Mucocele of the glands of Blandin-Nuhn--clinical, pathological, and therapeutical aspects. Oral and maxillofacial surgery 2011;15(1):11–3.
5. Harrison JD. Modern management and pathophysiology of ranula: literature review. Head & neck 2010;32(10):1310–20.
6. Zhao YF, Jia Y, Chen XM, Zhang WF. Clinical review of 580 ranulas. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology 2004;98(3):281–7.
7. Patel MR, Deal AM, Shockley WW. Oral and plunging ranulas: what is the most effective treatment? The Laryngoscope 2009;119(8):1501–9.
8. Zhao YF, Jia J, Jia Y. Complications associated with surgical management of ranulas. Journal of Oral and Maxillofacial Surgery 2005;63(1):51–4.
9. Chae BY. Traditional Korean medical eye, ear, nose, throat science Seoul: Chimmundang; 2004. p. 491.
10. Li GQ, Han Y. Three cases of ranula treated with Xīhuángwán. Information on traditional Chinese medicine 1994;(03):46.
11. Hé SM, Zhang L. Case report of ranula. Journal of traditional Chinese Medicine 1995;(06):375.
12. Sui J, Sui G. Mustard Seed treatment experience by phlegm. Journal of Traditional Chinese Medicine 1998;(04):197–8.
13. Chen T, Jiang SJ, Zheng F, Liu Q. One case treated with “Yin-fever” theory. Journal of Beijing University of Traditional Chinese Medicine(Clinical Medicine) 2013;(05):49–50.
14. Wang Y, Xia L, Li H. Ranula. Journal of Shandong traditional Chinese medicine 2001;20(2)
15. Traditional dermatology and surgery textbook compilation committee. Text of Traditional Korean dermatology and surgery Pusan: Sunwoo; 2007. p. 211–22.
16. ZHOU ZY. On Stagnated Heat. Journal of Nanjing University of Traditional Chinese Medicine 2006;22(5):273–6.
17. Park SW, Lee SW, Kangl’z BG, Leez I, Chou KH, Moon BS. The Effects of Dohongsamul-tang on Cytokine Production in Peripheral Blood Monocular Cells of Patients with Acute Cerebral Infarction. Korean J of Oriental Med 2006;27(4)
18. Lee JK, Song YK, Lim HH. Analgesic and anti-inflammatory effect of Scutellaria baicalensis. Korean Journal of Oriental Medicine 2007;28(4):124–35.
19. Steelman R, Weisse M, Ramadan H. Congenital ranula. Clinical pediatrics 1998;37(3):205–6.
20. Seo JH, Park JJ, Kim HY, Jeon SY, Kim JP, Ahn SK, et al. Surgical management of intraoral ranulas in children: An analysis of 17 pediatric cases. International journal of pediatric otorhinolaryngology 2010;74(2):202–5.

Article information Continued

Fig. 1

Photographs of Clinical Changes of Case 1.

A: 2013-05-11. Ranula on the right sublingual area, sized approximately 1.2cm×1.2cm.

B: 2013-08-31. No shrinkage was observed compared with A.

C: 2013-10-05. More than 50% shrinkage was observed.

D: 2013-11-26. The ranula was completely shrunk.

Fig. 2

Photographs of Clinical Changes of Case 2.

A: 2015-11-23. Sublingual mucocele sized 1.0×1.1cm was observed.

B: 2015-12-12. The size was reduced to nearly 0.5×0.8cm.

C: 2016-01-02. The size was approximately 0.4×0.6cm.

D: 2016-01-23. The sublingual mucocele nearly disappeared.

Fig. 3

Photographs of Clinical Changes of Case 3.

A: 2016-01-23. Plunging ranula about 3cm diameter was observed in the left submandibular area.

B: 2016-02-04. The diameter of the plunging ranula decreased to about 2.0cm.

C: 2016-02-22. The mass was not observed.

Fig. 4

Ultrasonography of Case 3 on 2016-03-09.

The ultrasonography revealed there was no mass around the left submandibular gland. The picture only showed trace of inflammation with low-echo.