The Effect of Drinking Alcohol on Bio-electrical Potential at Twelve Source Points: A Cross-over Study

Article information

J Korean Med. 2018;39(1):44-54
Publication date (electronic) : 2018 March 31
doi : https://doi.org/10.13048/jkm.18005
1Department of Meridian & Acupoints, College of Korean Medicine, Daejeon University
Correspondence to: 임윤경 (Yun-Kyoung Yim), Department of Meridian and Acupoints, College of Korean Medicine, Daejeon University 62, Daehak-ro, Dong-gu, Daejeon, 34520, Republic of Korea. Tel: +82-42-280-2610, Fax: +82-42-280-2641 E-mail: docwindy@dju.kr
Received 2018 February 23; Revised 2018 March 15; Accepted 2018 March 15.

Abstract

Objectives

The objective of this study is to investigate the effects of drinking alcohol on bio-electrical potential at twelve source points.

Methods

Twenty healthy adults were assigned to alcohol and water groups by a random cross-over design. Bio-electrical potential at twelve source points were measured before and after drinking alcohol or water and the change of bio-electrical potential was analyzed and compared between the alcohol and the water groups.

Results

Bio-electrical potential at LI4, ST42, KI3, PC7, TE4, GB40, LR3 in the alcohol group was significantly increased compared to those in the water group.

Conclusions

Drinking alcohol increased bio-electrical potential at source points of LI, ST, KI, PC, TE, GB and LR in healthy human subjects.

Fig. 1

Experimental protocol

Fig. 2

Change of Blood Alcohol Concentration (BAC)

Fig. 3

Effects of Alcohol on Bio-electrical potential at Twelve Source Points

Bio-electrical potential was detected at twelve source points before and after drinking alcohol or water. The detected signal was amplified and saved in the connected computer. The changes of bio-electrical potential at each time point was calculated and compared between the alcohol group and the water group. The scales on the y-axes are digital values converted with 16-bit resolution. Data were expressed as mean (n=20).

Red full circle: Alcohol group

Blue empty circle: Water group

* P < 0.05 vs Water group

General Characteristics of Subjects

Comparison of Bio-electrical Potential Change between the Alcohol Group and the Water group at Twelve Source Points

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Article information Continued

Fig. 1

Experimental protocol

Fig. 2

Change of Blood Alcohol Concentration (BAC)

Fig. 3

Effects of Alcohol on Bio-electrical potential at Twelve Source Points

Bio-electrical potential was detected at twelve source points before and after drinking alcohol or water. The detected signal was amplified and saved in the connected computer. The changes of bio-electrical potential at each time point was calculated and compared between the alcohol group and the water group. The scales on the y-axes are digital values converted with 16-bit resolution. Data were expressed as mean (n=20).

Red full circle: Alcohol group

Blue empty circle: Water group

* P < 0.05 vs Water group

Table 1

General Characteristics of Subjects

Mean ± SD
Age(year) 22.67 ± 2.24
Height(cm) 171.14 ± 6.62
Weight(kg) 68.66 ± 12.69
BMI(kg/m2) 23.33 ± 3.52
Body Temperature(°C) 36.08 ± 0.51
Systolic Blood Pressure(mmHg) 123.49 ± 14.07
Diastolic Blood Pressure(mmHg) 78.13 ± 11.52
Time after urination(h) 0.57 ± 1.01

Table 2

Comparison of Bio-electrical Potential Change between the Alcohol Group and the Water group at Twelve Source Points

Source Point P value (Alcohol vs Water)
LU9 0.126
LI4 0.005*
ST42 0.005*
SP3 0.129
HT7 0.070
SI4 0.129
BL64 0.134
KI3 0.011*
PC7 0.013*
TE4 0.013*
GB40 0.010*
LR3 0.023*