Comparison of Research Characteristics in Western, Chinese Traditional Medicine and Korean Medicine on Psoriasis
Article information
J Korean Med. 2021;42(2):72-81
Publication date (electronic) : 2021 June 01
doi :
https://doi.org/10.13048/jkm.21016
Received 2021 January 21; Revised 2021 March 9; Accepted 2021 March 16.
Abstract
Objectives
We compared research characteristics of western medicine, Chinese medicine and Korean medicine on causes, mechanisms, types, treatments and prevention of psoriasis.
Methods
For western medicine, “Psoriasis” was used as keyword on Pubmed, for Chinese medicine, “銀屑病” and “中医” on CNKI (China National Knowledge Infrastructure” and for Korean medicine, “건선” on OASIS. Keyword searches were done for papers and books published after 2010. For Chinese medicine, there were more in-depth searches done for “從血論 (血熱, 血瘀, 血燥)” and “陽虛症”.
Results
Western medicine puts an emphasis on the foci, and approaches it from molecular and genetic levels based on molecular biology; while it views psoriasis as a disease with multiple possible causes, it ultimately sees it as an inflammation that is immunity-mediated. Western medicine seeks to suppress cytokine in order to prevent and eliminate inflammation at each stage of treatment While they are effective short-term, psoriasis recurs shortly after. Chinese and Korean medicines categorize psoriasis as an internal comprehensive systemic diseases that encompasses the patient’s physical and mental characteristics, and defines it as a disease that has many causes and mechanisms such as “血熱, 血瘀, 血燥” and “陽虛”. They use herbal medicine, acupuncture, and lifestyle interventions to improve the overall health of the patient in addition to treating psoriasis. Treatments are effective, but it takes relatively longer to see results, and can recur.
Conclusion
In order for more progress to happen on psoriasis treatment, each branch of medicine must exchange knowledge and information more frequently.
Keywords: Psoriasis; Western medicine; Chinese Medicine; Korean Medicine; Comparison
Flow chart of psoriasis by Western Medicine, Chinese Traditional Medicine and Korean medicine
The Mechanism of psoriasis in Western Medicine
Concepts of Western Medicine on Psoriasis
Concepts of Chinese Medicine and Korean Medicine on Psoriasis
Comparison of Western Medicine, Chinese and Korean Medicine on Psoriasis
References
1. Youn JI. Psoriasis-An Atlas of Psoriasis 1st edth ed. Seoul: Korea Medical Book Publishing Company; 1996.
2. Lewis-Beck C, Abouzaid S, Xie L, Baser O, Kim E. Analysis of the relationship between psoriasis symptom severity and quality of life, work productivity, and activity impairment among patients with moderate-to-severe psoriasis using structural equation modeling. Patient Preference and Adherence 2013;7:199–205.
3. De Korte J, Sprangers MA, Mombers FM, Bos JD. Quality of life in patients with psoriasis: a systematic literature review. J Investig Dermatol Symp Proc 2004;9(2):140–147.
4. Wang R, Ding X, Xie F, Gong L, Yang Y, Wang W, et al. Metabolic syndrome affects narrow-band UVB phototherapy response in patients with psoriasis. Medicine 2017;96(50):8677–8677.
5. Lønnberg AS, Skov L. Co-morbidity in psoriasis: mechanisms and implications for treatment. Expert Review of Clinical Immunology 2017;13(1):37–34.
6. Korean Dermatology Association. Dermatology 5th rev. edth ed. Seoul: Ryo Moon Gak. P Co; 2008. p. 241.
7. Woo YR, Cho DH, Park HJ. Molecular Mechanisms and Management of a Cutaneous Inflammatory Disorder: Psoriasis. Int J Mol Sci 2017;18(12):2684.
8. Weatherhead SC, Farr PM, Reynolds NJ. Spectral effects of UV on psoriasis. Photochem Photobiol Sci 2013;12(1):47–53.
9. Trémezaygues L, Reichrath J. Vitamin D analogs in the treatment of psoriasis: Where are we standing and where will we be going? Dermatoendocrinol 2011;3(3):180–186.
10. Bai Y, Yang D, Wang Y, Qu X, Li YW, He JY. Clinical analysis on Quyin Granule in treating blood heat type of psoriasis. China Journal of Leprosy and Skin Diseases 2007;23(12):1065–1067.
11. Zhang DL, Shi P. 62 cases of Blood Heat Syndrome of Psoriasis Vulgaris treated by Liangxue Xiaoyin Mixture. Chinese Journal of Traditional Medical Science and Technology 2010;17(2):171–172.
12. Jing XM, Wu G, Qian N. Clinical observation and perception of Psoriasis Vulgaris treated by Huoxue Xiaoyin Decoction in 100 cases. Nei Mongol Journal of Traditional Chinese Medicine 2012;10:7.
13. Zhang YD. Discussion about Fundamental Treatment of Psoriasis 1st edth ed. Shanxi: Shanxi Science and Technology Publishing House; 2016.
14. Zhang YD. The Essence of Psoriasis is Accumulation. Chica Net of Traditional Chinese Medicine 2011. Jul. 22. Academic and Clinical Studies. p. 4.
15. Song P, Yang L, Wu ZK, Zou YH, Wang YY. Treatment of Psoriasis Vulgaris via New Perspective of Xuanfu Theory. Journal of Beijing University of Traditional Chinese Medicine 2009;32(2):136–138.
16. Song S, Choi J. A Study on the Trend of World Traditional Medicine and Key Area of Traditional Korean Medicine(TKM) R&D. Korea Journal of Oriental Medicine 2010;16(1):101–109.
17. Lee CY. Understanding Current Traditional Korean Medicine - Preliminary Study for Discussion on the Identity Issue of TKM. Korean J Oriental Physiology & Pathology 2010;24(5):758–769.
18. Yosipovitch G, Goon A, Wee J, Chan YH, Goh CL. The prevalence and clinical characteristics of pruritus among patients with extensive psoriasis. British Journal of Dermatology 2000;143(5):969–973.
19. Stinco G, Trevisan G, Piccirillo F, Pezzetta S, Errichetti E, di Meo N, et al. Pruritus in chronic plaque psoriasis: a questionnaire-based study of 230 Italian patients. Acta dermatovenerologica Croatica 2014;22(2):122–130.
20. Hancox JH, Sheridan SC, Feldman SR, Fleischer AB Jr. Seasonal variation of dermatologic disease in the USA: a study of office visits from 1990 to 1998. The International Society of Dermatology 2004;43:6–11.
21. Guttman-Yassky E, Krueger JG, Lebwohl MG. Systemic immune mechanisms in atopic dermatitis and psoriasis with implications for treatment. Exp Dermatol 2018;27(4):409–417.
22. Veale DJ, Fearon U. The pathogenesis of psoriatic arthritis. The Lancet 2018;391(10136):2273–2284.
23. Baurecht H, Hotze M, Brand S, Büning C, Cormican P, Corvin A, et al. Genome-wide Comparative Analysis of Atopic Dermatitis and Psoriasis Gives Insight into Opposing Genetic Mechanisms. The American Journal of Human Genetics 962015;:104–120.
24. Brito-Luna MJ, Villanueva-Quintero DG, Sandoval-Talamantes AK, Fafutis-Morris M, Graciano-Machuca O, Sanchez-Hernandez PE, Alvarado-Navarro A. Correlation of IL-12, IL-22, and IL-23 in patients with psoriasis and metabolic syndrome-Preliminary report. Cytokine (Online) 2016;85:130–136.
25. Furiati SC, Catarino JS, Silva MV, Silva RF, Estevam RB, Teodoro RB, et al. Th1, Th17, and Treg Responses are Differently Modulated by TNF-α Inhibitors and Methotrexate in Psoriasis Patients. Scientific Reportsvolume 9 2019;9(1):7526.
26. Moussali H, Bylaite M, Welss T, Abts HF, Ruzicka T, Walz M. Expression of hurpin, a serine proteinase inhibitor, in normal and pathological skin: overexpression and redistribution in psoriasis and cutaneous carcinomas. Experimental Dermatology 2005;14(6):420–428.
27. Jin L, Wang G. Keratin 17: A Critical Player in the Pathogenesis of Psoriasis. Medicinal Research Reviews 2014;34(2):438–454.
28. Becatti M, Barygina V, Mannucci A, Emmi G, Prisco D, Lotti T, et al. Sirt1 Protects against Oxidative Stress-Induced Apoptosis in Fibroblasts from Psoriatic Patients: A New Insight into the Pathogenetic Mechanisms of Psoriasis. International Journal of Molecular Sciences 2018;19(6):1572.
29. Lee YH, Song GG. Association between circulating 25-hydroxyvitamin D levels and psoriasis, and correlation with disease severity: a meta-analysis. Clinical and Experimental Dermatology 2018;43:529–535.
30. Kang DW, Han CY, Kim JD, Kim KS, Kim YB. A Proposal and Considerations for Treatment Approaches of Psoriasis. J Korean Med Ophthalmol Otolaryngol Dermatol 2020;33(3):99–114.
31. Reali E, Brembilla NC. Editorial: Immunology of Psoriatic Disease. Front Immunol 2019;10:657.
32. Hawkes JE, Chan TC, Krueger JG. Psoriasis pathogenesis and the development of novel targeted immune therapies. The Journal of Allergy and Clinical Immunology 2017;140(3):645–653.
33. Eberle FC, Brück J, Holstein J, Hirahara K, Ghoreschi K. Recent advances in understanding psoriasis. 2016;5:F1000.
34. Sbidian E, Mezzarobba M, Weill A, Coste J, Rudant J. Persistence of treatment with biologics for patients with psoriasis: A Real-World Analysis of 16,545 biologic-naïve patients from the French national health insurance database (SNIIRAM). Br J Dermatol 2019;180(1):86–93.
35. Kim WB, Jerome D, Yeung J. Diagnosis and management of psoriasis. Can Fam Physician 2017;63(4):278–285.
36. Mudigonda T, Dabade TS, Feldman SR. A review of targeted ultraviolet B phototherapy for psoriasis. J Am Acad Dermatol 2011;66(4):664–672.
37. Reichrath J, Saternus R, Vogta T. Challenge and perspective: the relevance of ultraviolet (UV) radiation and the vitamin D endocrine system (VDES) for psoriasis and other inflammatory skin diseases. The Royal Society of Chemistry and Owner Societies 2017;16:433–444.
38. Ford AR, Siegel M, Bagel J, Cordoro KM, Garg A, Gottlieb A, et al. Dietary Recommendations for Adults With Psoriasis or Psoriatic Arthritis From the Medical Board of the National Psoriasis Foundation A Systematic Review. JAMA Dermatol 2018;154(8):934–950.
39. Kim JH. Orignal Article : A Comparative Research of Eight Principle Pattern Identification - based on Zhang Jie-Bin, Cheng Guo-Peng, and Jiang Han-Tun. Journal of Oriental Medical Classics 2013;26(2):47–59.
40. Han JM, Yang WM. A Review on Korean Medicine and Personalized Medicine: Syndrome -based Personalized Medicine on the Basis of Syndrome Differentiation and Treatment. J Korean Med 2014;35(3):40–48.
41. Na CS, Jang GS, Sin YI, Kim JS, Hwang UJ. A clinical study according to Jang-Bu-Peon-Zheng. J Korean Med 1994;1528(2):143–155.
42. Cho EC, Kim KS. A Review on Patterns and Classification Criteria of Psoriasis by analyzing Chinese Theses. J Korean Med Ophthalmol Otolaryngol Dermatol 2020;33(2):112–129.
43. Lu CJ, Guo J. Exploration of the Nature of Psoriasis: Asthenia in Origin and Sthenia in Superficiality. Journal of Traditional Chinese Medicine 2016;57(20):1735–1740.
44. Song P, Wu ZK, Zou YH, Wang YY. New Ideas and Exploration of TCM syndrome differentiation and detoxification on Psoriasis Vulgaris. Chinese Journal of Information on Traditional Chinese Medicine 2009;16(12):90–91.
45. Baik YS. A Study on The Changes of Concept of Syndrome Differentiation in The History of Traditional Medicine -Focusing on meaning and process. J Korean Medical Classics 2014;27(4):133–151.
46. Fang X. Psoriasis China Medical Science Press; 2009.
47. Zhang YD. Treatment of Psoriasis Vulgaris with “Classical Prescription Eliminating Pathogenic Factor”. In : Interational(China Korea Japan) Conference of Classical Prescription-The second National Classical Prescription Forum and Advanced Apply Research Essays Collection; 2011; 05–26p. 172–191.
48. Zeng Jinrong, Luo Shuaihantian, Huang Yumeng, Lu Qianjin. Critical role of environmental factors in the pathogenesis of psoriasis. Journal of Dermatology 2017;44:863–872.
49. Singh RK, Lee KM, Jose MV, Nakamura M, Ucmak D, Farahnik B, et al. The Patient’s Guide to Psoriasis Treatment. Part 1: UVB Phototherapy. Dermatology and Therapy 2016;6(3):307–313.
50. Chandran V, Raychaudhuri SP. Geoepidemiology and environmental factors of psoriasis and psoriatic arthritis. Journal of Autoimmunity 2010;34:314–321.
51. Ammar-Khodja A, Benkaidali I, Bouadjar B, Serradj A, Titi A, Benchikhi H, et al. EPIMAG: International Cross-Sectional Epidemiological Psoriasis Study in the Maghreb. Dermatology 2015;231:134–144.
52. Park SJ. The Body(Mom) in East Asian Medicine. Philosophy of Medicine 2006;2:35–5.
53. Lee SY. What Should We do with Korea’s Biomedical Model of Medicine? - From Biomedical to Biopsychosocial Model. Korean Journal of Psychosomatic Medicine 2012;20(1):3–8.
54. Lee EH. The Principles of Sasang Constitutional Medicine Seoul: Tasan Cultural Foundation; 2015.
55. Kim JY, Kim WJ. Comparative Study of Oriental and Western Medicine 2nd rev. edth ed. Seoul: Gyechuk Munwhasa; 1994.
56. Park YB, Kim TH. Syndrome Differentiation and Diagnostics 1st edth ed. Seoul: Seongbosa; 1995.
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