Systematic Review and Meta-analysis of Electoacupunture Efficacy on Acute Gout
Article information
Abstract
Objectives
The objective of this study was to appraise the effect of electroacupuncture (EA) for the treatment of acute gout.
Methods
Since no suitable study could be found in the domestic database, we performed a literature search up to the end of December 2020 using four international electronic databases. Randomized controlled trials (RCTs) evaluating the effectiveness of EA in the treatment of acute gout were included. The risk of bias was evaluated from the Cochrane risk of bias tool.
Results
Eight appropriate RCTs were included and analyzed. Three evaluation tools were mainly used: Total Effective Rate (TER), Uric acid (UA), and Pain score (VAS). In the case of TER, in all eight cases, electroacupuncture alone and combined treatment showed a statistically significant level of improvement compared to Western medicine treatment. In the case of VAS score, electroacupuncture alone and combined treatment showed a more significant effect than Western medicine treatment. In the case of UA level, electroacupuncture combined treatment showed a more significant effect than western medicine treatment. Although not all three evaluation tools were used in all studies, the majority of studies showed that electroacupuncture was effective for acute gout patients.
Conclusions
The results of this study suggest that EA treatment may be effective for acute gout. It should be noted, however, that the studies included in this study were geographically biased, small in number, and mostly at high risk of bias. More well-designed studies are needed in the future.

Risk of bias summary (A) and graph (B)
A. +: low risk of bias, −: high risk of bias, ?: unclear risk of bias.

Meta analysis outcome of total efficiency rate between electroacupuncture alone or combined treatment vs. western medicine treatment.
A. Electroacupuncture vs. Western medicine treatment, B. Electroacupuncture+Blood-letting puncture vs. Western medicine treatment, C. Electroacupuncture+Blood-letting puncture+Moxibustion vs. Western medicine treatment, D. Electroacupuncture+Pharmacopuncture vs. Western medicine treatment.

Meta analysis outcome of pain score (VAS) between electroacupuncture alone or combined treatment vs. western medicine treatment.
A. Electroacupuncture vs. Western medicine treatment, B. Electroacupuncture+Blood-letting puncture vs. Western medicine treatment, C. Electroacupuncture+Blood-letting puncture+Moxibustion vs. Western medicine treatment, D. Electroacupuncture+Pharmacopuncture vs. Western medicine treatment.

Meta analysis outcome of uric acid between electroacupuncture alone or combined treatment vs. western medicine treatment.
A. Electroacupuncture vs. Western medicine treatment, B. Electroacupuncture+Blood-letting puncture vs. Western medicine treatment, C. Electroacupuncture+Blood-letting puncture+Moxibustion vs. Western medicine treatment, D. Electroacupuncture+Pharmacopuncture vs. Western medicine treatment.

Summary of the Randomized Controlled Trials of Electroacupuncture alone or combined treatment for acute gout
Acknowledgments
This research was supported by a grant from the Korea Health Technology R&D Project through the Korea Health Industry Development Institute (KHIDI), which is funded by the Ministry of Health & Welfare, Republic of Korea (grant number: HF20C0179).