A Case Report of a Patient with Long COVID Complaining of Cough and Sore throat Treated with Hyunggaeyungyo-tang and Saengmaek-san

Article information

J Korean Med. 2022;43(3):204-210

Publication date (electronic) : 2022 September 1

doi : https://doi.org/10.13048/jkm.22041

Daeso Branch office of Eumseong Public Health Center, Eumseong-gun, Republic of Korea

Correspondence to: 유창환, 57-16, Otae-ro, Daeso-myeon, Eumseong-gun, Chungcheongbuk-do, Republic of Korea, Daeso Branch office of Eumseong Public Health Center, tel: 043-871-2263, fax: 043-881-7032, E-mail: yuch3943@gmail.com

Received 2022 June 14; Revised 2022 August 9; Accepted 2022 August 16.

Abstract

Objectives

The purpose of this case study was to report the clinical improvement of Long COVID(cough, sore throat) treated with Korean herbal medicine(Hyunggaeyungyo-tang and Saengmaek-san).

Methods

To assess the treatment outcomes, I used the Visual analogue scale(VAS) to evaluate sore throat degree, and Leicester Cough Questionnaire Korean version(LCQ-K).

Results

After treatments, cough and sore throat were significantly improved with VAS and LCQ-K.

Conclusion

The Korean herbal medicine was effective in the treatment of patient who suffers Long COVID. This study suggested the possibility of Korean herbal medicine treatment for Long COVID.

Keywords: Long COVID; Korean herbal medicine; Public Health Center

Fig. 1

Change of Leicester Cough Questionnaire Korean version(LCQ-K)

Fig. 2

Chang of Sore throat Visual analogue scale(VAS)

Table 1

The Composition of Hyunggaeyungyo-tang

Table 2

The Composition of Saengmaek-san

References

1. Ministry of Health and Welfare. Coronavirus (COVID-19) Republic of Korea; Latest Updates. Accessed June 3, 2022. Available from: http://ncov.mohw.go.kr/en/bdBoardList.do?brdId=16&brdGubun=161&dataGubun=&ncvContSeq=&contSeq=&board_id= .

2. Ita K.. 2021;Coronavirus Disease (COVID-19): Current Status and Prospects for Drug and Vaccine Development. Arch Med Res. 52(1):15–24. https://doi.org/10.1016/j.arcmed.2020.09.010 .

3. Ministry of Health and Welfare. 코로나 확진자 후유증 조사 추진 및 빅데이터 개방(3.31.목, 정례브리핑) Accessed June 8, 2022. Available from: http://ncov.mohw.go.kr/tcmBoardView.do?brdId=3&brdGubun=31&dataGubun=&ncvContSeq=6532&board_id=312&contSeq=6532 .

4. Groff D., Sun A., Ssentongo A.E., Ba D.M., Parsons N., Poudel G.R., et al. 2021;Short-term and Long-term Rates of Postacute Sequelae of SARS-CoV-2 Infection: A Systematic Review. JAMA Netw Open 4(10):e2128568–e2128568. https://doi.org/10.1001/jamanetworkopen.2021.28568 .

5. 国家中医药管理局办公室. 新型冠状病毒肺炎诊疗方案(试行第九版) Accessed June 8, 2022. Available from: http://www.gov.cn/zhengce/zhengceku/2022-03/15/content_5679257.htm .

6. Pang W., Yang F., Zhao Y., Dai E., Feng J., Huang Y., et al. 2022;Qingjin Yiqi granules for post-COVID-19 condition: A randomized clinical trial. J Evid Based Med. 15(1):30–38. https://doi.org/10.1111/jebm.12465 .

7. An X., Peng B., Huang X., Jiang H., Xiong Z., Zhang H., et al. 2022;Ludangshen oral liquid for treatment of convalescent COVID-19 patients: a randomized, double-blind, placebo-controlled multicenter trial. Chin Med. 17(1):1–8. https://doi.org/10.1186/s13020-022-00602-x .

8. Lee S., Park J., jae Lee Y., hyoung Kim S., Lee J.. 2021;A Case Report of Taeeumin with Post COVID-19 Syndrome. J Sasang Const Med 33(4):32–42. https://doi.org/10.7730/JSCM.2021.33.4.32 .

9. Lee S.W., Kim T.H., Lee E.J., Jung I.C., Park Y.C., Lee S.W., et al. 2022;A Case Report on a Patient with Late Complications of COVID-19 Complaining of Dyspnea Treated with Korean Medicine Pulmonary Rehabilitation. J Korean Med. 43(1):171–179. https://doi.org/10.13048/jkm.22013 .

10. Han J.M., Jung I.C., Kang W., Kim S.S., Yeo Y., Park Y.C.. 2014;Reliability and validity of Leicester Cough Questionnaire Korean version. Chron Respir Dis. 11(3):147–152. https://doi.org/10.1177/1479972314536206 .

11. CDC. Long COVID or Post-COVID Conditions Accessed June 8, 2022. Available from: https://www.cdc.gov/coronavirus/2019-ncov/long-term-effects/index.html .

12. Hui K.P.Y., Ho J.C.W., chun Cheung M., chun Ng K., Ching R.H.H., ling Lai K., et al. 2022;SARS-CoV-2 Omicron variant replication in human bronchus and lung ex vivo. Nature. 603(7902):715–720. https://doi.org/10.1038/s41586-022-04479-6 .

13. Menni C., Valdes A.M., Polidori L., Antonelli M., Penamakuri S., Nogal A., et al. 2022;Symptom prevalence, duration, and risk of hospital admission in individuals infected with SARS-CoV-2 during periods of omicron and delta variant dominance: a prospective observational study from the ZOE COVID Study. Lancet (London, England). 399(10335):1618–1624. https://doi.org/10.1016/S0140-6736(22)00327-0 .

14. The society of Internal Korean Medicine. 2021. Clinical Practice Guideline of Korean Medicine-Common Cold KOONJA; Available from: https://nikom.or.kr/nckm/module/practiceGuide/view.do?guide_idx=161&menu_idx=14 .

15. Bae H., Kang W., Park Y.. 2008;Effectiveness of a Yeonkyopaedok-san Extract in the Treatment of The Common Cold: Results of a Community-based, Double Blind, Randomized Placebo Controlled Trial. Korean J Orient Physiol Pathol 22(1):234–245.

16. The whole country a college of Orental medicine. The joint textbook publish commission compilatioin. 2011. Herbology 2nd edth ed. Yonglimsa:

17. Park J.H., Hong S.U.. 2012;The Effects of Hyunggaeyungyo-tang of Suppression of iNOS Production on Mice with Allergic Rhinitis. J Korean Orient Med Ophthalmol Otolaryngol Dermatology. 25(1):12–21. https://doi.org/10.6114/jkood.2012.25.1.012 .

18. Baek H.J., Lee B.J., Jung S.K., Jung H.J.. 2016;Retrospective Study of Patients with Cough Treated with Eunhwayeongyo-tang. J of Int Korean Med. 37(6):961–77. https://doi.org/10.22246/jikm.2016.37.6.961 .

19. Spinou A., Birring S.S.. 2014;An update on measurement and monitoring of cough: what are the important study endpoints? J Thorac Dis 6(Suppl 7):S728–S734. https://doi.org/10.3978/j.issn.2072-1439.2014.10.08 .

20. Wang B., Liu Y., Wang Y., Yin W., Liu T., Liu D., et al. 2020;Characteristics of Pulmonary Auscultation in Patients with 2019 Novel Coronavirus in China. Respiration. 99(9):755–763. https://doi.org/10.1159/000509610 .

21. Arts L., Lim E.H.T., van de Ven P.M., Heunks L., Tuinman P.R.. 2020;The diagnostic accuracy of lung auscultation in adult patients with acute pulmonary pathologies: a meta-analysis. Sci Rep 10(1):7347. https://doi.org/10.1038/s41598-020-64405-6 .

22. National Institute for Korean Medicine Development. 2021. 2020 Korean Medicine Utilization Survey Available from: http://www.koms.or.kr/board/researchReport/view.do?post_no=1611682menu_no=21 .

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