A Case Report of a Patient with Normal tension glaucoma

Article information

J Korean Med. 2025;46(1):154-166
Publication date (electronic) : 2025 March 01
doi : https://doi.org/10.13048/jkm.25011
1Hunga Korean Medicine Clinic
2Risam Korean Medicine Clinic
Correspondence to: Han gioen, Hunga Korean Medicine Clinic. Sane, 10-gil, Jochiwon-eup, Seojong-si, Republic of Korea, Tel: +82-10-4422-9902, Fax: +82-0303-3442-1070, E-mail: hangi60@hanmail.net
Received 2024 October 3; Revised 2024 December 24; Accepted 2025 February 14.

Abstract

This is a case report on a patient in their early 60s who had been experiencing progressive normal-tension glaucoma in the left eye for 10 years. From June 2022, the patient was treated with prescriptions based on the Sanghanlon(Treatise on Sanghan) for two years. Six months after beginning treatment with this approach, the patient started receiving diagnoses from a local ophthalmology clinic indicating no further progression of glaucoma. This outcome was confirmed four times until May 2024, showing that the progression of glaucoma had stopped.

Fig. 1

OCT reports

OCT, Optical Coherence Tomography; ONH, Optic nerve head; OU, oculus uterque,; GCIPL, Ganglion cells inner plexiform layer

Fig. 2

Neovacular glaucoma

Fig. 3

Eye of patient with early glaucoma intraocular pressure26

Fig. 4

dry eye syndrome pupils suffering for many years

Fig. 5

Images of the Conjunctiva

2022 Treatment Prescription

2023 Treatment Prescription

2024 Treatment Prescription

Composition of the Prescription

Body Heat(°C)

C/D Ratio&Total RNFL results of Right eye

C/D Ratio&Total RNFL results of Left eye

References

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3. Kim HS., Kim HM., Seong GJ., Yu YS.. 2020. Text of Ophtahlmology Seoul: Ilchokak. p. 297–340.
4. Health Insurance Review and Assessment Service (HIRA). 2021. Diseases in daily life. Statistics of medical treatment activities publication registration number G000EPI-2021-163 [serial online] 2021. Dec. [citied 2021 Dec. 23]. 1(1)Available from: https://www.hira.or.kr/bbsDummy.do?pgmid=HIRAA020045010000&brdScnBltNo=4&brdBltNo=2361&pageIndex=1&pageIndex2=1.
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6. Han GE., Kang EJ., Lee GS.. 2023;A Case of Korean Herbal Medicine Treatment for Normal Tension Glaucoma using Go-Bang. J Korean Med 44(3):102–116. https://doi.org/10.13048/jkm.23034.
7. Yakjing Yoshimasu todo original. 2021;Kim, Jong-oh Mulgogisup :54–362.
8. Choi YA., Joo BC.. 2018;Retinal Nerve Fiber Layer Thickness Messured by Spectral Domain Optical Coherence Tomohrapy in Healthy Koreans. J Korean Ophthalamol Soc 59(6):537–42. https://doi.org/10.3341/jkos.2018.59.6.537.

Article information Continued

Fig. 1

OCT reports

OCT, Optical Coherence Tomography; ONH, Optic nerve head; OU, oculus uterque,; GCIPL, Ganglion cells inner plexiform layer

Fig. 2

Neovacular glaucoma

Fig. 3

Eye of patient with early glaucoma intraocular pressure26

Fig. 4

dry eye syndrome pupils suffering for many years

Fig. 5

Images of the Conjunctiva

Table 1

2022 Treatment Prescription

Prescription period Prescription name Reason for prescription Dosage instructions Progress
June Chijahubak-tang
Bongnyeongeum
Bloodshot eyes
Chest discomfort
Glucose instability
Each medicine, twice daily, for a total of four doses. Ocular foreign body sensation and vitreous floaters improved by 90%.
Jul. to Sep. Chijahubak-tang
Gyulpidaehwangbakcho-tang
Bloodshot eyes
Chest discomfort
Chijahubak-tang: 3 times a day
Gyulpidaehwangbakcho-tang: Once a day(before bed time)
The ocular foreign body sensation resolved.
Vitreous floaters in the right eye diminished.
The erythema and visible blood vessels on the left cheek nearly disappeared.
Oct.to Dec. Sohamhyung-tang
Gyulpidaehwangbakcho-tang
Dyspepsia
Bloodshot eyes
Chest discomfort
Each medicine, twice daily, for a total of four doses. Glare in the left eye decreased.

Table 2

2023 Treatment Prescription

Prescription period Prescription name Reason for prescription Dosage instructions Progress
Jan. to Feb. Sogunjung-tang
Gyulpidaehwangbakcho-tang
Recurrent discharge in the right eye
Abdominal muscle rigidity
Hang-bae-gang
Gyeol-hyung
Dry eye syndrome
Sogunjung-tang: 3 times a day
Gyulpidaehwangbakcho-tang: Once a day
The glare is present.
Dryness in the eyes remains.
Mar. to May Sogunjung-tang
Bongnyeongeum
Morning lacrimation
Glare in the left eye occurs when tired
Hyeop-ha-bi
Abdominal muscle rigidity
Sogunjung-tang: Twice a day
Bongnyeongeum: Once a day
The glare in the left eye worsened and then decreased.
Rigidity of the left masseter and temporalis muscles, Hang-bae-gang persist.
Jun. Sogunjung-tang
Bongnyeongeum
Rigidity of the left masseter and temporalis muscles
Hang-gang
Sogunjung-tang: Twice a day
Bongnyeongeum: Once a day
Rigidity of the left masseter and temporalis muscles, Hang-gang persist.
The glare is present.
Jul. Gejigajakyak-tang
Taeksa-tang
Pain and swelling in the lower abdomen during activities. Each medicine, twice daily, for a total of four doses. The glare and the blurred vision in the eyes decreased.
Aug. Taeksa-tang
Gyejigahubakhaengja-tang
Rigidity of the left masseter and temporalis muscles Each medicine, twice daily, for a total of four doses. The pain and swelling in the lower abdomen decreased.
Urine output increased. The glare is almost gone. The blurred vision remains.
Oct. Gyejigahubakhaengja-tang
Gyejigagalgeun-tang
Daehamhyunghwan
Blurred vision
Hang-bae-gang
Gyeol-hyung
Gyejigahubakaengja-tang: Twice a day
Gyejigagalgeun-tang: Once a day
Daehamhyunghwan: Once a day
Night pain and swelling in the lower abdomen recurred.
Nov. Taeksa-tang
Gyejigagalgeun-tang
Daehamhyunghwan
Pain and swelling in the lower abd
Hang-bae-gang
Gyeol-hyung
Taeksa-tang: Twice a day
Gyejigagalgeun-tang: Once a day
Daehamhyunghwan: Once a day
The pain and swelling in the lower abdomen resolved.
The blurred vision decreased
Dec. Daehamhyung-tang
Sogunjung-tang
Hang-bae-gang
Gyeol-hyung
Tearing in cold places
Hyup-ha-bi
3 times a day Gyeol-hyung decreased.
Tearing decreased.

Table 3

2024 Treatment Prescription

Prescription period Prescription name Reason for prescription Dosage instructions Progress
Jan. Daehamhyung-tang
Sogunjung-tang
Gyeol-hyung
Tearing in cold places
3 times a day Table Gyeol-hyung, tearing in cold places remain.
Feb. Gyejigagalgeun-tang
Daehwangmokdanpi-tang
Hang-bae-gang
Pain and swelling in the lower abdomen
Gyejigagalgeun-tang: Twice a day
Daehwangmokdan-tang: Once a day
Hang-bae-gang, the pain and the swelling in the lower abdomen decreased.
Mar. Sogunjung-tang
Daehwangmokdan-tang
Increased tearing in the left eye Sogunjung-tang: Twice a day
Daehwangmokdanpi-tang: Once a day
The tearing remains.
The swelling in the lower abdomen resolved.
Apr. Daehwangmokdan-tang Swelling in the lower abdomen 3 times a day Repetitive swelling in the lower abdomen.
Jun. Daehwangmokdan-tang
Baekduong-tang
Gyeol-hyung
Abodomen pain
Daehwangmokdanpi-tang: Once a day
Baekduong-tang: Twice a day
Right abdomen pain decreased.

Table 4

Composition of the Prescription

Prescription Name Ingredients of Herbal Medicine Prescribed (g/1 day)
Chijahubag-tang Gardeniae Fructus 6, Magnoliae Cortex 8, Ponciri Fructus Immaturus 8g
boglyeong-eum Ginseng Radix 6, Poria Sclerotium 6, Atractylodis Rhizoma 6, Ponciri Fructus Immaturus 4, Aurantii Fructus Immaturus 5, Zingiberis Rhizoma Recens 8g
Gyulpidaehwangchoseog-tang Aurantii Fructus Immaturus 2, Rhei Radix et Rhizoma 2, Natrii Sulfas 4g
Sohamhyung-tang Coptidis Rhizoma 3, Pinelliae Tuber 5, richosanthis Fructus 8g
Sogunjung-tang Cinnamomi Ramulus 8, Glycyrrhizae Radix et Rhizoma 6, Zizyphi Fructus 6, Paeoniae Radix 12, Oryzae Gluten20g
Gyejigajagyag-tang Cinnamomi Ramulus 8, Paeoniae Radix 12, Glycyrrhizae Radix et Rhizoma 4, Zingiberis Rhizoma Recens 6, Zizyphi Fructus 6g
Gyejigahubaghaengja-tang Cinnamomi Ramulus 8, Paeoniae Radix 6, Glycyrrhizae Radix et Rhizom 4, Zingiberis Rhizoma Recens 6, Zizyphi Fructus 6, Magnoliae Cortex 4, Armeniacae Semen 6g
Gyejigagalgeun-tang Cinnamomi Ramulus 8, Paeoniae Radix 12, Glycyrrhizae Radix et Rhizom 4, Zingiberis Rhizoma Recens 6, Zizyphi Fructus 6, uerariae Radix 40g
Taegsa-tang Alismatis Rhizoma 10, Atractylodis Rhizom12g
Daehamhyung-tang Rhei Radix et Rhizoma16, Natrii Sulfas 10, Euphorbiae Kansui Radix 1g
Daehamhyung-hwan Euphorbiae Kansui Radix, Rhei Radix et Rhizoma, Lepidii seu Descurainiae Semen, Natrii Sulfas, Armeniacae Semen
Daehwangmokdan-tang Rhei Radix et Rhizoma 8, Moutan Radicis Cortex 3, Persicae Semen 6, Natrii Sulfas 8, Benincasae Semen 10g
Baekduong-tang Pulsatillae Radix 4, Coptidis Rhizoma 6, Phellodendri Cortex 6, Fraxini Cortex 6g

Table 5

Body Heat(°C)

Time Jun. 2022 Nov. 2022 Apr. 2023 Dec. 2023 Jun. 2024

Meridian
L-eye(closed) 36.9 36.7 36.4 35.8 36.1

R-ye(closed) 36.7 36.5 36.4 35.8 36.1

L-Taeyang 37 36.8 36.4 36.3 36.4
EX-HN5

R- Taeyang 36.8 36.6 36.4 36.3 36.4
EX-HN5

L-Wangol 37.8 37.5 37 36.4 36.7
GB12

R- Wangol 37 37 36.4 36.8 36.6
GB12

Table 6

C/D Ratio&Total RNFL results of Right eye

Mar. 2018 Apr. 2020 Jun. 2021 May. 2023 Jun. 2024
Average c/d ratio 0.80 0.85 0.79 0.80 0.84
Vertical c/d ratio 0.83 0.82 0.82 0.80 0.81
AverageRNFL Thickness 73 68 70 71 70
RNFL Symmetry 69 71 53 78 69

C/D ratio, Cup/Disc ratio; RNFL, Retinal nerve fiber layer

Table 7

C/D Ratio&Total RNFL results of Left eye

Mar. 2018 Apr. 2020 Jun. 2021 May. 2023 Jun. 2024
Average c/d ratio 0.81 0.80 0.82 0.80 0.78
Vertical c/d ratio 0.83 0.84 0.83 0.81 0.77
Average RNFL Thickness 72 73 71 72 72
RNFL Symmetry 69 71 53 78 69

C/D ratio, Cup/Disc ratio; RNFL, Retinal nerve fiber layer