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JKM > Volume 42(3); 2021 > Article
Kim, Ju, Kim, Park, Yun, and Park: A Systematic Review of effect on Heat-sensitive Moxibustion for Benign Prostatic Hyperplasia



The aim of this study is to investigate the effect of Heat-sensitive Moxibustion on Benign Prostatic Hyperplasia


We searched articles from Academic Journals(CAJ) online databases, Oriental Medicine Advanced Searching Integrated System (OASIS), Searching key words were ‘前列腺增生’, ‘熱敏灸’ and ‘열민구’, ‘전립선비대’. The search range included randomized controlled trials (RCTs). Among the articles published to 2020, 10 articles were found. After review the title, abstract and original, 3 articles were selected finally to rule out treatment combined with completely different treatments.


The Heat-sensitive moxibustion at acupoints in the treatment of Benign prostatic hyperplasia were significantly superior to control group after treatment in the symptoms of patients, IPSS, QOL, PVR and Qmax(P<0.05). The Heat-sensitive moxibustion can significantly reduce the incidence of temporary urinary incontinence after Transurethral resection of the prostate(TURP) and improve life quality and satisfaction of patients(P<0.05). The individualized desensitization saturated time and amount of Heat-sensitive moxibustion is superior effective to general amount and time of traditional moxibustion in the total effective rate, IPSS, Ru and Qmax(P<0.01) for Benign prostatic hyperplasia.


Heat sensitive moxibustion directly transfer heat to the source of a disease. So it can be considered as a good treatment for Benign prostate hypertrophy. It was also shown a better effect on BPH compared to traditional moxibustion, According to the thermo principles of tumor, if the tumor cell’s death temperature of 43°C is reached, that can cause tumor degeneration. Therefore I think Heat sensitive moxibustion can be applied to various tumor disease. The results of this study could be applied to clinical treatment of BPH. However, additional large-scale clinical researches should be conducted.

Fig. 1
Study selection process of PRISMA flowchart
Fig. 2
Risk of bias summary and graph
Table 1
Data of Clinical Curative Effect of Heat-sensitive Moxibustion for Benign Prostatic Hyperplasia
First Author (Year) Intervention(n) Duration Main Outcomes Results
Experimental Group(n) Control group(n)
Wang W, Chen Q, Li Q, Liu L, Wang X, Yan ZR(2019)
  1. Tamsulosin Hydrochloride Sustained Release Capsules

  2. Choose the two acupoints on heat sensitive acupoint-Guanyuan, Zhongji, Shenshu, Mingmen, Ciliao with the strongest heat sensitivity to moxibustion, once a day, each time from moxibustion to heat sensitivity disappeared (30)

Tamsulosin Hydrochloride Sustained Release Capsules (30) 4 weeks IPSS, QOL, PVR, Qmax After the treatment, the effective rate of the treatment group, 96.7% and that of the control group, 76.7%. There was a significant difference between two groups (P <0.05). After treatment, The International Prostate Symptom Score(IPSS), Quality of Life score(QOL), Postvoid residual urine volume(PVR) and Maximum urine flow rate(Qmax) were superior to control group(P<0.05).
Xie B, Zhang X(2020)
  1. Nursing mind map on temporary urinary incontinence after prostate hyperplasia surgery

  2. Heat-sensitive moxibustion on heat sensitive acupoint-Shenque, Qihai, Guan Yuan, Zhongji (30)

  1. Nursing mind map on temporary urinary incontinence after prostate hyperplasia surgery(30)

During Jan 2016–Dec 2017 incidence of urinary incontinence, urine leakage times, volume, life quality score of incontinence, Zung’s anxiety scale The difference in incidence of urinary incontinence between the groups was statistically significant (P<0.05). There were statistically significant differences between the groups in urine leakage times score, duration of urinary incontinence, life quality score of urinary incontinence, urine leakage volume score, Zung anxiety score(P<0.05)
Zhou M, Huang XB, Chen RX(2018) A: Desensitisation saturated dosages of Heat-sensitive moxibustion Lower abdomen (in the area of Zhongji-Guanyuan-Qugu) and sacrum (in the area Mingmen-Cilian-Yaoshu), apply moxibustion at a distance of about 3 cm from the skin (32) B: Dosages of Traditional Moxibustion Lower abdomen (in the area of Zhongji-Guanyuan-Qugu) and sacrum (in the area Mingmen-Cilian-Yaoshu), apply moxibustion at a distance of about 3 cm from the skin (32) A,B: 35 times treatment(a total of 30 days) Curative effect, Ru, Qmax, IPSS The total effective rate of A after treatment and 6 months follow-up were 89.5%(29/32), 90.1%(30/32), which were better than B, 69% (22/32) and 69.3%(22/32) respectively(P<0.01). IPSS and bladder residual urine(Ru) of two groups after treatment and 6 months follow–up were significantꠓly decreased(all P<0.05). The Qmax rate was significantly increased (all P<0.05). The IPSS and Ru of A group after treatment and 6 months follow–up were significantly decreased(all P<0.01) than B. The Qmax was significantly increased than B(P<0.01).
Table 2
Zung’s self-rating anxiety scale
問 题 回 答

沒有或偶爾 有時 經常 總是如此
我覺得比平時容易緊張和著急 (焦慮)
我覺得我可能將要發瘋 (發瘋感)
我感覺容易衰弱和疲乏 (乏力)
我覺得心平氣和,並且容易安靜坐著 (靜坐不能)
我臉紅發熱 (面部潮紅)


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